Todd Moody wrote:
>
> Alex Shvartsman wrote:
>
> >[Cordain] Finally, at the molecular level saturated fats
> >have been shown numerous times to down regulate the LDL receptor by their
> >direct influence upon gene transcription for the LDL receptor proteins.  This
> >evidence is the "smoking gun" which most lay readers are unaware or don't
> >understand.
> >
> >
>
> This is correct, and a Nobel prize was awared for this discovery some
> years back.
>
> The unresolved issue, however, is whether an increase in LDL is, in
> itself, cause for concern.  Cordain and the vast majority of scientists
> think it is...

No, even Cordain admits that this is unknown. He said so on this list.
He admits to the strong possiblility that a high SFA low carb diet would
increase LDL while at the same time decreasing small dense LDL and
thereby possibly decreasing atherosclerosis. To me this makes his
dietary plan somewhat of a house of cards.