<<Disclaimer: Verify this information before applying it to your situation.>> Hi everyone, I recently wrote regarding my children's blood test results. They had all come out positive for the IgG antigliadin antibody test but were negative for the IgA and EMA test and they also were not IgA deficient so this indicates the IgA and EMA were accurate tests. I asked "why bother testing for any other blood test other than the EMA because of the frequent false positives on the IgG " and I received a response from Dr. Vijay Kumar of IMMCO Diagnostics, Inc. He discussed the three types of tests for CD (EMA, ARA and AGA). The EMA and ARA detect IgA antibodies but since there are some patients who are IgA deficient, and these tests come out negative, his laboratory will do repeat tests on patients whose IgG test is positive by testing for the presence of IgG class autoantibodies to EMA and ARA. He says this will identify all CD subjects who are IgA deficient. Because of this he believes all the tests are important. I also received a posting from someone who tested positive on both antigliadin antibody tests (IgG and IgA) and negative on the EMA (endomysial antibody) and had a positive biopsy. This certainly changed my thinking quite a bit. I always thought the EMA was the definitive test and I see now there are always those few exceptions. There is always the chance of a test being incorrectly done so it's not good to depend on just one test. As a final thought, when I have my children retested a few years from now, I will request that the doctor orders all the tests. I will also ask him to write on the order where I want the blood samples to be sent. These tests are usually sent out to a larger laboratory and the only way to get a local lab to send it to where you want it sent is to have the doctor write it on the order. Thanks to all who wrote. Barb from NE Ohio