<<Disclaimer: Verify this information before applying it to your situation.>> Hello all, Here are the results of "to take or not to take Centrum in case of low B-12": 15 answers were received. 8 of them recommended not to take Centrum. 7 said that there are no problem with taking Centrum. The most recommended way for taking B-12 vitamins is in Sublingual form (under the tongue). Thanks for all of you who answered me. Doodi.