<<Disclaimer: Verify this information before applying it to your situation.>> I have long believed in the value of vitamin C for a lot of very good scientific reasons. Since I am able to control my conditions well (asthma and severe allergies along with gluten intolerance) and stay in very good health without heroic measures, I haven't really done serious self experimentation with vitamin C. I eat lots of fruit and vegies. I just got hold of buffered vitamin C powder, as calcium ascorbate. This is a form of C that is non acidic, which I think becomes important if you wish to take large amounts of it. In addition, it provides 50 mg of readily absorbable calcium with every gram (1000 mg) of C. I immediately started a little experiment to at least get close to +tissue saturation+ which i guess to be about 5-6 grams a day. I mix it in my drinks, fruity flavored herbal teas, after the tea cools. I did not exceed bowel tolerance. However I did feel appreciably better the first day; I slept better, woke up fresher, feel generally sharper. I also made sure to take more magnesium to balance out the calcium I am getting. This is actually a covenient way for me to get calcium as I avoid dairy products. At about 5 cents a gram, this is not overly expensive and i will probably cut back some after a week. Magnesium is thought to be used at a ratio of 1 to 2 relative to calcium. in normal humans. My studies show that for allergics/asthmatics, the best ratio may be more like 1 to 1, or maybe even more magnesium than calcium. National nutritional studies show many US americans low in magnesium by RDA standards. Magnesium oxide is the cheapest, most widely available and least well absorbed.