<<Disclaimer: Verify this information before applying it to your situation.>> My daughter has a genetic brittle bone disorder (26 fractures and she's 9 years old). Her particular problem is caused by her not making enough collagen. Our family doctor recently went to Sweden for a cartilage transplant. When he came back, he recommended that my daughter take this supplement. Since he's never ever recommended any kind of supplement and rolls his eyes when I mention them, that makes me think he was either told to take this by the Swedish surgeon or when told to take something else, he asked about my daughter specifically. We had a little trouble finding it--we get it from my son's chiropractor from a company called Nutriwest. Nutriwest is in Wyoming and they are VERY concerned about allergens in their supplements. They would know about the gluten-free status of their products with great confidence and certainty. Nutriwest will only sell to health care practitioners. They carry an extensive array of vitamin, mineral, herbal, amino acids, and all kinds of supplements along with either Chinese or homeopathic remedies. Their reputation is for keeping their supplements as pure as possible. It's too soon to tell if she's had any improvements from the supplement. Jean Jasinski