<<Disclaimer: Verify this information before applying it to your situation.>> May I suggest that you might be getting small amounts of gluten? Marsh et. al. have demonstrated microvascular leakage at the site of rectal-gluten challenge, in celiac patients. > the next 1 and 1/2 hours trying to control the out >of control bleeding I was doing in order to put me back together. They >immediately did clotting tests and mine were all normal, but I was even >having occassional nose bleeds with very bright bleeding. I had had >surgery in June without any bleeding problems. Anyone have any ideas? If you have been getting gluten in your diet, there is some evidence to suggest intestinal bleeding is common among celiacs ingesting gluten. It was reported in a NEJM article earlier this year, but I can't put my hand on the article just now. > All >the Dr's asked about my CD. They gave me large doses of Vit K in the OR, >but without any changes(but normally would take 24-48 hrs for changes). I >am to see a haemotologist. I also have lost large amounts of hair >recently. The hair loss might also suggest gluten ingestion via increased circulating antibodies, and molecular mimicry. (This is a hypothesis where the antibodies to substances from outside the body are developed, and the antigen is similar, in molecular structure, to self-tissues that an autoimmune attack ensues.) Alterations in cholesterol, and sex hormone-binding globulins have also been associated with gluten ingestion (Gates). There is a very complex constellation of possibilities, many of which are suggestive of gluten. An antibody test might shed some light on your current g-f status. I am not a doctor. These are the musings of a fellow celiac, but I hope they are helpful. Sincerely, Ron Hoggan References: 1. Marsh MN, _Immunopathology of the Small Intestine_ John Wiley & Sons, Toronto, 1987; pages 374-377. 2. Ensari, et. al. "Time-course adhesion molecule expression in rectal mucosa of gluten-sensitive subjects after gluten challenge" Clin Exp Immunol 1993; 92: 303-307. 3. Marsh, MN "Gluten, Major HIstocompatibility Complex, and the Small Intestine" Gastroenterology 1992; 102: 330-354. 4. Ronda et. al. "Selectivity of recognition of variable (V) regions of autoantibodies by intravenous immunoglobulin (IVIg)" Clinical Immunology & Immunopathology 1994; 70(2): 124-128. 5. Van der Wal, et. al. "Adhesion molecules on the endothelium and mononuclear cells in human atherosclerotic lesions" Am J Pathology 1992; 142(6): 1427-1433. 6. Davies et. al. "The expression of the adhesion molecules ICAM-1, VCAM-1, PECAM, and E-selectin in human atherosclerosis" Journal of Pathology 1993; 171(3): 223-229. 7. Languino, et. al. "Regulation of leukocyte-endothelium interaction and leukocyte transendothelial migration by intercellular adhesion molecule 1-fibrinogen recognition" Proceedings of the National Assembly of Sciences of the United States of America 1995; 92(5): 1505-1509. 8. Lutz WJ "The Colonisation of Europe and Our Western Diseases" Med Hypoth 1995; 45: 115-120. 9. Vuoristo, et. al. "Metabolism of Cholesterol and Apolipoprotein B in Celiac Disease" Metabolism 1993; 42(11): 1386-1391. 10 Gates et. al. "Association of dietary factors and selected plasma variables with sex hormone-binding globulin in rural Chinese women" Am J Clin Nutr 1996; 63: 22-31.