<<Disclaimer: Verify this information before applying it to your situation.>> Hi Everyone At the time of my diagnosis, I had my biopsy, which was negative. The locum of the consultant sugessted trying a self imposed GF diet for six months to see if there was any improvement, my blood chem was way out particularly folic acid, B5, and B12. After six months, he confirmed I had coeliac disease. Sometimes the biopsy can prove negative he said. If in doubt...........