<<Disclaimer: Verify this information before applying it to your situation.>> After speaking with several Upjohn representatives, I received confirmation that MOTRIN, in all forms of the over the counter varities, is gluten free. This was confirmed with Customer Rep. Tammy, and the physician with the Medical Division (left a message on machine, did not leave name). The starch bases they use are derived from Corn. Fran Gillespie