<<Disclaimer: Verify this information before applying it to your situation.>> Does anyone have any insight into a positive Anti-Nuclear Antibody blood test (specifically mine is 1:1280) and its relationship to gluten intolerance? I originally had a diagnosis of a Lupus like syndrome, although I didn't meet enough of the criteria for acutual Lupus. Years ago I had a diagnosis of Chronic Fatigue Syndrome...which seemed to eventually go away. My daughter is biopsy proven Celiac. I have been on the Gluten Free Diet for 6 months and noticed a marked improvement in my health (running up to 6 miles a day), had the Celiac blood panel done...(IgG slightly abnormal), but my ANA remains positive. Anyones thoughts (especially any doctors) would be appreciated. Jane Oswaks