<<Disclaimer: Verify this information before applying it to your situation.>> After reading the article, "Recombinant Antibody Blocks Grass Pollen Allergen", http://www.medscape.com/viewarticle/441178 , I posed the question, "Can recombinant antibodies be engineered to prevent gluten reactions?" I received no responses, so I took it upon myself to see if I could find some answers to the question. I ran across the following on-going joint European celiac research project: http://immunology.no/cd/eu The project's background and detail information is extremely interesting: http://immunology.no/cd/eu/background.html Current focus on gluten antigens that cause celiac disease is centered on deamidated gluten peptides which stimulate T cell responses associated with celiac disease. Deamidated refers to a process which modifies orginal gluten peptides by converting glutamines into glutamic acid. At least 11 such deamidated gluten peptides have been identified. This research is exciting because it can lead to better ways of determining gluten toxicity in foods and possible new ways to treat celiac disease. But to answer my orginal question about engineering antibodies to prevent gluten reactions, it would seem to me possible that recombinant antibodies might be engineered to block these deamidated gluten peptide antigens and prevent the T cell stimulation and response which leads to celiac disease. The future of celiac disease treatment is wide open. *Support summarization of posts, reply to the SENDER not the CELIAC List*