<<Disclaimer: Verify this information before applying it to your situation.>> Since I was the one who orginally posted the info aboiut using l=glutamine for leaky gut several years ago, I feel I must correct the mis-information that has been going around about the dosage. BOTH the internist and nutrionist said the same thing.....WITH EACH Meal take one l-glutamine capsule and one probiotics complex CAPSULE. You'll need to stay on that dosage AT LEAST a year. Then, you can lower the dosage to once or twice a day for maintenance FOR LIFE> [sorry about all those caps, but.......]