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Hi!

Just a quick little question.  We all know that zonulin is a protein that
regulates the tight junctions.  We also know that we celiacs apparently
produce too much zonulin, which increases our intestinal permeability;
i.e., opens the gates to the tight junctions.  My question is simply does
any one know what "good" purpose is served by zonulin?  Another way of
saying this, is why do we want our tight junctions to open in the first
place (in any healthy person without an autoimmune disorder)?   Thanks!

Warm Regards, Janet Kline
Charlotte, NC
The Queen City
www.charlotte-celiac-connection.org

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