<<Disclaimer: Verify this information before applying it to your situation.>>

I believe the discussion of Olestra & it being *not recommended* for
those with Celaic Sprue has occured on this list... enclosed is a list
of technical info to add substance to that conversation.

Assessment of Nutritional Effects of Olestra, a Nonabsorbed Fat
Replacement: Summary

426 John C. Peters, Kenneth D. Lawson, Suzette J. Middleton and Keith C.
Triebwasser. J. Nutr. 127: 1719S-1728S, 1997.

ABSTRACT Olestra is a zero-calorie fat replacement intended to replace 100%
of the fat used in the preparation of savory snacks.  Olestra can affect the
absorption of other dietary components, especially highly lipophilic ones,
when ingested at the same time.  The potential effects of olestra on the
absorption of essential fat-soluble and water-soluble dietary components have
been investigated in pigs and in humans.  In these studies, subjects were fed
daily amounts of olestra up to 10 times the estimated mean intake from savory
snacks and the olestra was eaten each day of the studies.  In real life,
snacks are eaten on average five times in a 14-d period.  Olestra did not
affect the availability of water-soluble micronutrients or the absorption and
utilization of macronutrients.  Olestra reduced the absorption of fat-soluble
vitamins A, D, E and K; however, the effects can be offset by adding
specified amounts of the vitamins to olestra foods.  Olestra also reduced the
absorption of carotenoids; analysis of dietary patterns showed that in real
life the reduction will likely be <10%.  Any effect on vitamin A stores
caused by a reduction in carotenoid uptake is offset by the addition of
vitamin A to olestra foods.  Because of the olestra-to-nutrient ratios fed
and the nutritional requirements of the test subjects, the effects of olestra
on nutritional status of subgroups of the population are unlikely to be
different than those measured in the studies.  An analysis of lipophilicity
showed that olestra is unlikely to significantly affect the uptake of
potentially beneficial phytochemicals from fruits and vegetables.  Some
people eating large amounts of olestra snacks may experience common GI
symptoms such as stomach discomfort or changes in stool consistency, similar
to symptoms accompanying other dietary changes.  These symptoms present no
heath risks.  J.  Nutr.  127:  1719S-1728S, 1997.

(This info was posted on a diabetes support list)

The info clarifies that olestra does interfere with absorption, which is
already a problem for those w/ Sprue.

Fran/ Oregon US of A
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