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Date: | Thu, 9 Mar 1995 13:41:28 GMT |
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<<Disclaimer: Verify this information before applying it to your situation.>>
From Dr. Reichelt in reply to my post yesterday, in which I wondered
whether the amounts of gluten in mother's milk is significant:
3/9/95 4:38 PM
Subject: Trace amount of protein in milk.
From: Kalle Reichelt,[log in to unmask]
To: William Elkus
Hi.
It should be stressed that the amount are small. However, the point is
that even trace amounts can be important because if the proteins are not
properly broken down peptides will accumulate. After all the uptake of
proteins from the gut into blood has also been demonstrated:Husby et al
(1985) passage of undegraded dietary antigen into the blood of healthy
adults .Scand j Immunol 22: 83-92.
Other references in brief :
Bloch KJ et al (1979) gastroenterology 77:1039-1044.
Thomas et al (1974)Immunology 27:631-639.
Walker WA et al (1974) gastroenterol 67: 531-550.
Because gluten contains at least 15 opioid sequences per molecule
(Fukudodme S-I and Yoshikawa M (1991) Opioid peptides derived from wheat
gluten :Their isolation and characterization .FEBS Letters 296:107-111.)
It is therefore clear that one molecule could theoretically give 15
opioids . This means that trace amount of peptide could quickly become
very important.
Cheers Tiny
K. Reichelt
Pediatric Research Institute
N-0027 Oslo, Norway
Tel: +47 22 86 90 45
Fax: +47 22 86 91 17
E-mail: [log in to unmask]
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