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Subject:
From:
Bob Fritz <[log in to unmask]>
Reply To:
Evolutionary Fitness Discussion List <[log in to unmask]>
Date:
Thu, 13 Feb 2003 18:43:40 EST
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In a message dated 2/13/2003 2:11:34 PM Pacific Standard Time,
[log in to unmask] writes:


>  regard to the inadequacy of the paleo diet, once one has fully
> replenished glycogen stores (both hepatic and muscluar) additional carbs
> will be stored as fat...in a hyperinsulinemic condition this may happen
> even
> before glycogen loading.  You assert that it is difficult or impossible to
> meet these nees on a paleo diet.  A 200lb man can store a maximum of about
> 400 gm of carbs as glycogen. One need only to eat an apple and orange at
> each of three standard feedings and

Hepatic glycogen stores deplete rapidly, replete slowly.  Liver glycogen is
essentially zero upon waking, and is depleted quite rapidly during exercise.
 Muscle glycogen stores are more stable.  After a 24 hour fast, muscle
glycogen is almost unchanged, liver glycogen very low.  Muscle and liver
glycogen are quite different, and maximal storage of CHO in muscle is easily
achieved compared to liver. Liver glycogen is poorly refilled by glucose
alone vs gluconeogenic precursors + glucose.  G. Brooks, McGarry and others
have done nice work regarding this area.  Tim Noakes also.

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