<<Disclaimer: Verify this information before applying it to your situation.>> I just received this message from Medscape regarding new indicators for first degree relatives. If you are interested, see the following. http://gastroenterology.medscape.com/14952.rhtml SEROLOGIC, GENETIC MARKERS IDENTIFY CELIAC DISEASE IN FIRST-DEGREE RELATIVES OF PATIENTS Both serologic markers and the human lymphocyte antigen class II extended DQ2 (HLA-DQ2) haplotype are useful markers for screening first-degree relatives of patients with celiac disease for the disorder. http://gastroenterology.medscape.com/14952.rhtml