<<Disclaimer: Verify this information before applying it to your situation.>> Hi List: Thanks for all the replies. Here is what "you" had to say about digestive enzymes: ...I take Peptidase by Apothecure. They have a Web site: apothecure.com. My physician recommended these enzymes, and I have happily gained 9 pounds on them. (I was down to 92 pounds). ...I take digestive enzymes and never had a problem with them.. The brand is Prevail 1-800-248-8085 It says on the label free of gluten. ...I have been taking "Creon" for the past 10 - 12 years. ...I believe that digestive enzymes are one the most important things a Celiac person can do, other than avoiding gluten intake. Because Celiacs are prone to having digestive problems of many kinds, it is imperative to make sure that we are breaking down proteins properly. If proteins are not broken down by the necessary enzymatic response, polypeptides, macro-molecules of proteins can then be released into the system through intestinal permeability (Leaky Gut syndrome). Both of these aforementioned scenarios are very common among Celiacs. Once these macro-molecules are in the bloodstream, there are many different manifesting disease states depending upon a particular persons bio-chemical predisposition. I was actually diagnosed as having bipolar disorder as a result of chemicals that pass the blood-brain barrier and interact with neurotransmitters, this also is a well documented scenario for the Celiac. There is a particular member of this group, who I believe is one of the founders of the listserve, Don Wiss who has an extensive database of information that can be accessed from his web site: www.panix.com/~donwiss The best in my opinion is called GNC Preventive Nutrition, Multi-Enzyme Formula, Capsules. Note* it says no gluten on the bottle!! ... I have been taking "Multi-Enzyme" by The Vitamin Shoppe. I do not take them regularly, but I try to take them after a heavy meal, or when I suspect I may have eaten a contaminated product. I do not get a reaction to them (they are labeled as gluten-free), but then again, I can not be sure that they really help. ...I don't think it's a digestive enzyme, but I take Acidophilus. This is a "good bacteria" I think. It seems to do wonders for me. ...I have occasionally been taking papaya enzymes for about 2 years. recently I switched to a brand called 'natural factors" it has papain and amylase, as well as bromelain. label reads contains no gluten. I recommend it. ...I have used Freeda's Parvenzymes for years. I always carry a bottle of them with me. I chew on a couple after I eat and it makes digesting much easier. I had one response whereby someone stated: "I went through that and it didn't do any good". Thanks for all the responses. It seems that many of you feel that digestive enzymes are important! Kelly