<<Disclaimer: Verify this information before applying it to your situation.>> Two respondents thanked me for sharing. Six respondents advised sedation. Four respondents were utterly appalled. One respondent scolded me for scaring everyone. One respondent said that my experience gave them courage. I tried to be as objective as possible in my description. I would do it without sedation again in a heart beat. However I do not advise it for the squeamish or little kids. It really was no big deal. There was no pain just a little discomfort. Now here is the heartening part: no one has to do it without sedation! If I had insisted on sedation, I would have been sedated. There are three options, 1) nothing at all 2) sedation 3) full anaesthetic. Mine was the worse case scenario. To the one poster: (the biopsy did not give me a Hiatal hernia I have known that I have one for seven years now). I am sorry if I caused anyone any grief. I will say one thing, I would certainly take the biopsy over being sick like a dog and loosing 30 lbs in two months, any day !