<<Disclaimer: Verify this information before applying it to your situation.>> I received this post off the list and thought I should share it: -vance I don't have any idea about Lactose content as I don't have a problem about that. However, my pharmacist did call the company and verify the following with them: Prilosec 20 is not gluten free however, Prilosec 40 mg is gluten free, (how weird).