HI ANDREW I believe the program you are looiking for is chess master 2000, I am not blind but my husband Al is. Anyway I had this program and it would read off each play the computer moved if I wanted it too, and would read off my moves if i wanted it too. I don't know if it works with a screen reader as we have not bought one yet, however it is a very interactive program that not only teaches people to play chess but would set skill levels. I t talks alot. I believe that you could enjoy this program very much it is a cdrom program that works with windows and came installed on my old packard bell computer. I have seen it in the stores however. Good luck diane griffith