<<Disclaimer: Verify this information before applying it to your situation.>> I've been lactose-intolerant free for four years and have had no problems from the Glucophage since that initial episode in January. I was diagnosed with niddm March of '97 and started the Glucophage in June of that same year. I guess the important thing to remember is that each diabetic is unique and a particular routine that works well for one may be inadequate for another. Lana