<<Disclaimer: Verify this information before applying it to your situation.>> Report on QUESTIONS 2 12 list members responded QUESTIONS 2. 11 of them were predisposed to different kinds of allergic reactions and had gastro-intestinal problems. Many of them reported improvement of allergic condition on GF diet. Thus, this group had "celiac-like syndrome". Table 1. Comparison of celiac and celiac-like patients. Celiac group Celiac-like group G1: 36 G2: 12 N1 í1 +/- m1 N2 í2 +/- m2 t Celiac disease 36 100.000 0.000 12 0.000 0.000 Patch-shaped foci of hyperkeratosis 33 27.273 7.873 12 0.000 0.000 P<0.05 Visible steatorrhoea 36 52.778 8.438 12 16.667 11.237 P<0.05 Thus, celiacs had more steatorrhoea (stool leaves traces) - a sign of malabsorption and patch-shaped hyperkeratosis. It is possible to suggest that pathogenesis of allergy (at least some forms of allergy) involves some mechanisms common with pathogenesis of celiac disease. Dear list members, I know that you are tired of my QUESTIONS, but to finish this investigation I want to collect a group of people without diagnosed CD and without significant allergic reactions. To help this, please, ask your relatives or friends to respond QUESTIONS 3. Michail Valivach, MD QUESTIONS 3 1. Name (or pseudonym). Sex. 2. Birth date Stature Weight 3. Please, confirm that you are not a celiac and not predisposed to allergic reactions 4. Do you have chronic (lasting more than 2 months) of frequent (more than 4 episodes in a year) infectious and noninfectious inflammatory diseases? Yes, No, I can not answer If "Yes", please answer the following questions: a. Do you have chronic or frequent respiratory infections? Yes, No, I can not answer If so, are you easily infected during epidemics Yes, No, I can not answer and/or you have your own chronic or relapsing infection (for instance, chronic bronchitis, tonsillitis etc) Yes, No, I can not answer List the infections: b. Do you have or had asthma? Yes, No, I can not answer 5. Do you have any skin diseases? Yes, No, I can not answer If "Yes", please, list their diagnoses: 6. Are you predisposed to allergic reactions? Yes, No, I can not answer If "Yes", please, give more information 7. Do you have any diseases of the digestive system (additionally to CD)? Yes, No, I can not answer Please, list them: 9. The highest body temperature during the last 3 years: 10. Are you predisposed to long lasting (more than 14 days) fever? Yes, No, I can not answer 11. Fatigue 12. Please, describe you skin. Do you have: a. Constant or episodic hair loss Yes, No, I can not answer b. Dry or tarnished hair Yes, No, I can not answer c. Early turning gray (before 30) Yes, No, I can not answer d. Predisposition to dandruff Yes, No, I can not answer e. Fragility of the nail walls Yes, No, I can not answer f. Fragility of the nails Yes, No, I can not answer g. Dryness of the lips Yes, No, I can not answer h. Cyanosis of the lips Yes, No, I can not answer i. General skin dryness Yes, No, I can not answer j. Dryness and/or scaling and/or irritation - in the nasolabial region Yes, No, I can not answer - of the elbows and/or knees Yes, No, I can not answer - above the brows (including dandruff) and/or around the eyes Yes, No, I can not answer - of the hands (especially after water exposure) Yes, No, I can not answer - of the cheeks Yes, No, I can not answer - of the nose Yes, No, I can not answer - of the ears Yes, No, I can not answer k. Follicular hyperkeratosis (perifollicular accentuation). That means small dry skin elevations around the hair follicles. Yes, No, I can not answer l. Cyanotic, marbled skin Yes, No, I can not answer m. Scaling dermatitis (like eczema) Yes, No, I can not answer n. Red spots with dryness and/or scaling and/or irritation Yes, No, I can not answer o. Predisposition to acne (black heads) Yes, No, I can not answer p. Bad tolerance to sun burns Yes, No, I can not answer q. Skin itching Yes, No, I can not answer r. Chronic skin candidiasis (yeast infection) Yes, No, I can not answer s. Feet cyanosis Yes, No, I can not answer t. Patch-shaped foci of hyperkeratosis (foci of dry and thick skin) Yes, No, I can not answer 13. Please, describe the tongue: a. Enlarged tongue with the teeth imprints Yes, No, I can not answer b. Smooth ("polish") tongue Yes, No, I can not answer c. Hypertrophy of the tongue papillae (small round elevations) Yes, No, I can not answer d. Dry bright-red tongue Yes, No, I can not answer e. Cracks or folds on the tongue Yes, No, I can not answer f. Irritation and/or brown cover of the tongue base Yes, No, I can not answer g. Dryness of the mucous membranes Yes, No, I can not answer h. Gum bleeding after teeth brushing Yes, No, I can not answer 14. Gastrointestinal tract: a. Unpleasant smell from the mouth Yes, No, I can not answer b. Pains in the tip of the stomach Yes, No, I can not answer c. Heartburn Yes, No, I can not answer d. Sour and/or bitter and/or nasty belch Yes, No, I can not answer e. Unpleasant sensations below the ribs on the right Yes, No, I can not answer f. Unpleasant sensations below the ribs on the left Yes, No, I can not answer g. Pains in the upper abdomen or nausea on fasting Yes, No, I can not answer h. Feeling bloated after moderate amounts of food Yes, No, I can not answer i. Intestinal murmur after food Yes, No, I can not answer j. Intestinal murmur after milk Yes, No, I can not answer k. Hemorrhoids Yes, No, I can not answer l. Liquid or semi-liquid stool very often Yes, No, I can not answer m. Intensive urges to defecate Yes, No, I can not answer n. Stool leaves traces on the lavatory bowl Yes, No, I can not answer o. Undigested food in stool very often Yes, No, I can not answer p. Fragmented ("sheep's") stool Yes, No, I can not answer q. Constipation Yes, No, I can not answer r. Stool with sour smell Yes, No, I can not answer s. Stool with rotten smell Yes, No, I can not answer