<<Disclaimer: Verify this information before applying it to your situation.>> Hi everyone, I have recently had all my children tested with the antigliadin antibody IgG blood test (which all came out positive) and this was followed by the endomysial antibody(EMA) and the IgA antigliadin antibody (which all came out negative). In addition, my two youngest were tested for IgA deficiency and neither were deficient. My oldest son underwent a biopsy and thankfully, it was negative. After going through all of this, I am wondering when testing first degree relatives of Celiacs, if it is necessary to do the IgG blood test as there are so many false positives. I was right in not rushing into having my younger children biopsied just on the result of this one blood test (which was originally ordered by my gastro doctor ) and having the IgA and EMA done before making a decision. Before posting this, I inquired of a few doctors, why a person might have a positive IgG and negative everything else and one answer given by Dr. Horvath was that "the IgG antibody to different food allergens (not only gluten) may occur frequently in everybody at least temporarily. The reason is not so well known. Generally it is an "innocent" finding. It means that the immune system of the gut reacted to the food antigen, but there is no further immune reaction leading to mucosal damage." It was also recommended to repeat the blood tests every few years or if there are symptoms in my children. My question to the medical professionals on the list is - why bother repeating any blood tests other than the EMA? If this is the definitive test, shouldn't this be the only one done for follow-ups? I am also thinking, that when testing first degree relatives, the IgG test should not even be done as there are so many false positives. The EMA with testing for IgA deficiency should be enough. I would like to provide my doctor with any views on this as I think only ordering the IgG tests was a mistake on his part. It caused me great anquish as I waited for the results on the other more specific tests. I might add that my children were also very upset. Thanks, Barb from NE Ohio