<<Disclaimer: Verify this information before applying it to your situation.>> The converse question of Downs Syndrome and CD is: If Downs Syndrome children are so much more likely to get CD than the general population, then does untreated CD in mothers have a tendency to be a factor in the development of children born with Down's Syndrome? Just a question, since as far as I know, we do not have an answer for Downs Syndrome, other than it is more prevalent in older mothers. (Perhaps my data is outdated) If there was a correlation, then it might be an added incentive for my untested daughters to get checked out before having more children. They don't seem to feel it is a priority for themselves, but are very conscientious about their children's welfare. Carol in Nj