<<Disclaimer: Verify this information before applying it to your situation.>> After being GF to the best of my ability for 5 months I recently underwent, at the direction of my gastroenterologist, a one week gluten challenge at the end of which the small bowel biopsy was performed and blood was drawn for antibody testing. I previously tested negative for the antibodies, but that was after being GF for one month. Test results: Biopsy: Normal, no signs of inflammation (took tissue from 3 locations) Anti-Endomysial: Negative Anti-Gliaden: 14.4 (normal range is from 0 to 7) Anti-Reticulin: Titer was 1:80 (in 'normal' people I understand it should be zero (negative)) The doctor is rather confident that I don't have Celiac Sprue, but what exactly these results indicate is uncertain, except that I will remain on a gluten free diet so I can be a productive member of society. My intestinal symptoms of gas and diarrhea kicked in within 3 days of beginning the challenge, and my fatigue and lethargy weren't far behind. With the tiredness comes a drop in my resting pulse and blood pressure and nearly constant dizzyness. I did not monitor body temperature. It's been a week and a half since I resumed my GF diet and I am recovering with the same gradual speed as I have in the past. I expect to feel relatively normal in about another 1 1/2 weeks. Has anyone experienced odd results such as these and how was that interpreted? Thanks for you input! -- Margaret Pratt E-mail: [log in to unmask] Toxicology Program http://www.orst.edu/~prattm/ Oregon State University