<<Disclaimer: Verify this information before applying it to your situation.>> I would like some information regarding refractory sprue. I have checked Sam Adams website and followed various links but was unable to find any real information. (I am not terrifically computer literate yet.) I would greatly appreciate more information, specifically answers to the following questions: 1) What (other than not following the GF diet) can cause refractory sprue? 2) What, if anything, is the treatment for refractory sprue and is it a cure or does it simply alleviate symptoms? 3) Is there a typical prognosis for refractory sprue? 4) What would be the recommended method of diagnosing refractory sprue (i.e. to rule out another ailment such as irritable bowel syndrome)? Please e-mail me privately and I will summarize for the list. Thank you. Jane (in VA, USA) [log in to unmask]