<<Disclaimer: Verify this information before applying it to your situation.>> Hi, Thanks for your post. It sounds VERY familiar. I have had a negative biopsy, negative serum test, but I feel wonderful on a gluten free, lactose free diet!! My gastro doc said that I may have patchy areas of damaged villi in my small intestine or maybe I'm in the beginning stages of the disease. At the time of the testing I had been gluten free for three weeks. My Dr. said that the villi couldn't repair themselves that quickly but since then I've read that they can repair quickly. He recommended that I stay gluten free and occaisionally try introducing gluten. I've been gluten free for three months and I feel absolutely wonderful. I've struggle with irritable bowel syndrome (or so they thought) for the last four years. It's nice to finally feel good. Since my testing (april) I have found out that I have a great uncle with Celiac disease (paternal) and an aunt (paternal) that had the same symptoms that I had. She never was diagnosed and died of intestinal cancer when she was in her fourties (Yikes). I know it's difficult not having a definite diagnosis. I have lots of concerns about this especially when I need to get my two children the serum tests. I'm wondering if the insurance companies will pay for the tests when I technically don't have a diagnosis. I joke with my husband , who is very glad to have me feeling better, that I'm a "Celiac Wanna Be." Of course this is a silly statement because who wants to have this problem!! I guess humor can be helpful at times! Hang in there. Let me know how it's going from time to time. Tonya Davis Washington State