<<Disclaimer: Verify this information before applying it to your situation.>> Lisa, and others: Enjoyed the Reuters article, Lisa, thanks! But their attributing all the neurological problems to an immune reaction may be a little shortsighted. This is my persuasion because of what I've seen in my family, that some people cannot handle gluten who test negatively on IG tests. My daughter and father fall into that category, and I might, too, but I have not been tested. We are all MUCH improved neurologically off gluten and milk products. I believe the reason for the improvement is explained by the opiate excess theory of autism, but none of us is autistic. My daughter had gross motor delays, I have had autoimmune problems, and my father has alzheimers. I guess I should say I believe in this caveat: if you test negative on the celiac test suite, do not assume that you will have no benefit from eliminating wheat. Try the special diet and decide for yourself. It's not that hard, and if it will help you, believe me, you will know within a week or so, maybe sooner! Enthusiastically gluten-free non-celiac, Susan Owens PS. By the way, my husband's cousin, who has ankylosing spondylitis, has been gluten-free for three weeks, and had a challenge last week with a piece of raisin bread. She said she woke up thinking she was having a heart attack with her heart racing. (She guesses now it was heartburn.) The next day she had diarrhea all day long. I don't know if she has ever been tested for celiac but I do know she has had lots of GI workups, all negative.