<<Disclaimer: Verify this information before applying it to your situation.>> Comment from Don Kasarda, Albany, California Probably the first published description (I think there have been others since) of constipation in celiac patients before diagnosis was published in 1972, where 12 out of 112 children were noted to have been constipated at some time before diagnosis. The exact reference follows: Bridget Egan-Mitchell and Brian McNicholl. 1972. Constipation in childhood celiac disease. Archives of Disease in Childhood 47:238-240.