<<Disclaimer: Verify this information before applying it to your situation.>> The following was posted to the autism mailing list/newsgroup: On Thu, 19 Oct 1995, Toril Myrtveit <[log in to unmask]> wrote: >I just went to a week-end cooking course (for g/c-free foods), where I >learned that most people with casein intolerance didn't tolerate soy either. >(no soy-milk, no soy-margarine, no soy sauce,...) This was all new to me. >Supposedly, the soy-intolerance is due to the caseinates being similar in >soy and cow-milk. Sounds wacko to me, and there was no medical experts there >to explain why this should be so. Being curious, I sent this to Dr. Reichelt, and this is his reply: Date: Sat, 21 Oct 1995 09:21:04 +0100 From: [log in to unmask] (Kalle Reichelt) Subject: Soy intolerance Hi. The evidence for this is very dubious. Sometimes when children are allergic (IgE mediated) to milk their antibodies may cross react with soy bean proteins. <Therefore if we are not satisfied with the progress of children on gluten & casein free diet, soy protein has been removed too. I do not find any definite effect of this.) Exorphins have not been found from soy-proteins. The only bioactive peptides found so far are antioxidant peptides from Soybean beta-Conglycinin (1), and an immunomodulating peptide (2). All proteins do give rise to peptides during uptake from the gut, and if not broken down or otherwise increased they may inhibit the break down of other dietary and also endogenous peptides. The reason for this has been extensively discussed (3), and is due to peptides generally being good peptidase inhibitors. Therefore increasing the intake of peptidases (not proteinases) in enterosoluble capsules like those from papaya would be a good idea. Preliminary data look promising. References: 1: Chen H.M et al (1995) Structural analysis of antioxidative peptides from Soybean Beta-Conglycinin. j Agricult and Food Chem 43: 574-578. 2: Yamauchi F and Suetsuna K (1993) Immunological effects of dietary peptide derived from soybean protein. J Nutr Biochem 4: 450-457. 3: LaBella FL et al (1985) Administration of peptides inhibit the degradation of enodgenous peptides. The dilemma of distinguishing direct from indirect effects. Peptides 6: 645-660. All the best Cheers TINY K. Reichelt Pediatric Research Institute N-0027 Oslo, Norway Tel: +47 22 86 90 45 Fax: +47 22 86 91 17 E-mail: [log in to unmask]