<<Disclaimer: Verify this information before applying it to your situation.>> Um...how it can it be a psychological effect when I ate it accidentally? In each case, I had the reaction and then discovered that vanilla extract had been used. No problem with vanilla from beans or extracted from non-gluten sources. I suppose we could try our gluten-testing kit on some vanilla, but frankly, it was so expensive I hate to waste it on something that I *know* affects me. I agree that anecdotal evidence is not evidence but in the case of sprue it's often all we have. In the face of all the contrary advice and information we're given--sometimes from the same organization!--I prefer to play it safe, especially when my experience supports the conclusions. Wendy, [log in to unmask]