People suffering from schizophrenia have brains that lose the ability to forget or ignore as much as they normally would. Without forgetting, they lose the ability to extract what's meaningful out of the immensity of stimuli the brain encounters. http://scienceblog.com/45099/scientists-afflict-computers-with-schizophrenia-to-better-understand-the-human-brain/ Findings suggest that exaggerated prediction-error signaling in schizophrenia intermingles and corrupts narrative memories when incorporated into long-term storage, thereby disrupting narrative language and producing fixed delusional narratives. If further validated by clinical studies, these computational patients could provide a platform for developing and testing novel treatments. http://www.biologicalpsychiatryjournal.com/article/PIIS0006322311000126/fulltext www.peoplewho.org