<<Disclaimer: Verify this information before applying it to your situation.>> Recently a lady with celiac disease asked Cynthia Kupper of the Gluten Intolerance Group and myself about a product called GlutenEase http://www.enzymedica.com/products/GlutenEase?PHPSESSID=acc87d6bc3f8e5be 44a7912d2b077745. Below is Cynthia's response: This product is not advertised for persons with celiac disease but for persons with gluten intolerance that is not celiac disease. It will not stop the damage that is happening in the GI tract for persons with celiac disease. Cynthia Kupper, RD, CD Executive Director Gluten Intolerance Group of North America(r) 31214 - 124 Ave SE, Auburn WA 98092-3667 Phone: 253-833-6655 Fax: 253-833-6675 www.GLUTEN.net <http://www.gluten.net/> www.GFCO.org <http://www.gfco.org/> www.GlutenFreeRestaurants.org And this is a response I got from Dr. Alessio Fasano about this product: Hi Betty, I must agree with you on this. As far as I know, there have been no clinical trials to date to validate this stuff. The safest and most conservative way to approach this is to check the government web site for clinical trials (www.clinicaltrial.gov) and use the key word 'celiac disease". If the product did not go through the rigorous scrutiny of FDA, I would not trust it. Alessio Alessio Fasano, M.D. Professor of Pediatrics, Medicine, and Physiology Director, Mucosal Biology Research Center University of Maryland School of Medicine Health Science Facility II Room S345 20 Penn St. Baltimore, MD 21201 Response I received from Dr. Peter Green on GlutenEase: It has been very difficult to find enzymes that digest the fragments of gluten that are toxic to people with celiac disease. Nevertheless, researchers have been working on this aspect of treatment for many years. Several enzymes are currently being rigorously tested to ensure that they do not create any allergic or immunological reaction in the body since they are foreign proteins being introduced into the digestive tract. While the supplements being marketed make no claims for treating CD, they are still advising people to take their products without this rigid testing of efficacy and effectiveness. In short, it is doubtful that they are effective and unclear as to whether they are safe. Most people with celiac disease are careful about the foods they put in their mouth. They should be equally - or even more careful - about over-the-counter supplements. This product is being directed to unsuspecting gluten intolerant people who are eager to take a pill and go back to eating gluten. This product is not what some may think or hope it is. Betty Barfield President, North Texas GIG <mailto:[log in to unmask]> *Support summarization of posts, reply to the SENDER not the CELIAC List* Archives are at: Http://Listserv.icors.org/SCRIPTS/WA-ICORS.EXE?LIST=CELIAC