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A 2-year study in the July 2006 Endoscopy showed older celiac patients on 
a gluten-free diet have an incomplete histological recovery even after 2 
years.  "Only the younger patients (5 - 30 years) showed significant 
improvement of histology within 12 months (P < 0.034); older patients (>30 
years) showed histological improvement but this was not statistically 
significant, even after 24 months on a GFD."  This study was also 
previously discussed in an article by Dr. Antonio Tursi in the Spring 2006 
Celiac.com Scott-Free Newsletter.

This also means increased intestinal permeability and associated problems 
such as liver damage may continue to be a lasting problem in older 
patients beyond 2 years on a GF diet.

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Endoscopy 2006 July; 38(7): 702-707
Endoscopic and histological findings in the duodenum of adults with celiac 
disease before and after changing to a gluten-free diet: a 2-year 
prospective study 
Tursi, A.; Brandimarte, G.; Giorgetti, G. M.; Elisei, W.; Inchingolo, C. 
D.; Monardo, E.; Aiello, F.

Table of Contents:
< http://www.thieme-connect.de/ejournals/toc/endoscopy > 

Abstract (Paste address together on one line.):
< http://www.thieme-connect.de/ejournals/abstract/endoscopy/doi/10.1055/s-
2006-925178 > 

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