To reply to a digest, insert the relevant message header; don't reply to the digest header ------------------------------------------------------------- On Mon, 15 Mar 2004 10:00, John Cogburn wrote: >I haven't gotten the full-text yet, but this article really seems to >support our view of evolutionary fitness. > >J Appl Physiol 96: 3-10, 2004; 10.1152/japplphysiol.00757.2003 > ... > >Eating, exercise, and "thrifty" genotypes: connecting the dots toward an >evolutionary understanding of modern chronic diseases John Thanks for this advice. To get an idea of what the article probably includes, have a look at: http://www.sciencedaily.com/releases/2002/07/020716080427.htm This reports on Chakravarthy's 2002 article "Waging War on Physical Inactivity: Using Modern Molecular Ammunition Against an Ancient Enemy," in the Journal of Applied Physiology The web report begins: "The results of the most extensive research investigation into the relationship between chronic health conditions and physical inactivity have been released by a team of "obesity sleuths." They conclude that today's skyrocketing levels of chronic diseases are due to the collision between the body's total gene complement of a set of chromosomes -- programmed 10,000 years ago to anticipate physical exertion, and the inactivity endemic to 21st century sedentary societies. Nutritional "thrifty genes" may further exacerbate the deterioration of the human body, which takes the form of common, chronic disorders, once thought to be rare...." Chakravarthy also wrote (with Frank Booth, lead author in the 2002 paper, "Exercise - Hot Topics" in 2003. See: http://www.harcourt-international.com/catalogue/title.cfm?ISBN=1560535687 The page begins: "This exciting and timely volume presents the principles for the primary prevention of chronic conditions by exercise. It discusses the health consequences of inactivity, the biologic basis for the benefits of physical activity, and presents strategies for combating the sedentary- living epidemic. Packed with figures, graphs, and tables for easy access. Presents guidelines for exercise and tips on counseling patients and encouraging them to undertake exercise programs "Key Points" sections focus on the most important aspects of exercise "Pros" and "cons" feature delineates new and controversial issues An introductory section on "What's Hot" focuses on the cutting-edge aspects Contents: I: Defining the Problem 1. From Hunting and Gathering to 7-11s and TV 2. Definitions 3. Genetic Considerations 4. Physical Activity Deficiency 5. Children's Health Endangered II: The Means to Action 6. Health Benefits of Physical Activity 7. Caloric Balance and Expenditure 8. Physical Activity Prescription 9. Counseling Patients About Undertaking Physical Activity 10. Weight Loss Counseling 11. Promotion of Routine Daily Physical Activity III: Biological Basis For Chronic Diseases Caused By Physical Inactivity 12. Health Consequences of Physical Inactivity 13. Cardiovascular Diseases 14. Metabolic Diseases 15. Cancer 16. Ageing 17. Bed Rest/Spinal Cord Injury 18. Pulmonary Diseases 19. Inflammation/Immune Dysfunction 20. Neurological Disorders 21. Musculoskeletal Disorders 22. Gastroesophageal Reflux Disease 23. Women's Health 24. Regulation of the Human Genome Through Physical Activity 25. Inactivity: A Fat Chance of Being Healthy Keith ----------------------------------------------------------------- The FAQ for Evolutionary Fitness is at http://www.evfit.com/faq.htm To unsubscribe from the list send an e-mail to [log in to unmask] with the words SIGNOFF EVOLUTIONARY-FITNESS in the _body_ of the e-mail.