LISTSERV - PALEOFOOD Archives - LISTSERV.ICORS.ORG

Approved-By: [log in to unmask]
MIME-Version: 1.0
Content-Type: text/plain; charset="iso-8859-1"
Content-Transfer-Encoding: 8bit
Importance: Normal
Message-ID:  <[log in to unmask]>
Date:         Thu, 15 Aug 2002 02:18:46 -0700
Reply-To: Low-Carbohydrate Technical Discussion              <[log in to unmask]>
Sender: Low-Carbohydrate Technical Discussion              <[log in to unmask]>
From: Leanne Ridley <[log in to unmask]>
Subject:      Re: [LOWCARB] Medline story about lowcarb diets causing kidney
              stones?
To: [log in to unmask]
In-Reply-To:  <[log in to unmask]>

I am SO unimpressed by such a biased, sloppy, unprofessional, intellectually
dishonest study. 2 weeks! it's not enough to determine *anything* except
loss of water weight!

Recall the 2 studies posted by Nicolai, both being 6 week studies (much more
reliable):

1) J Nutr 2002 Jul;132(7):1879-85
A ketogenic diet favorably affects serum biomarkers for cardiovascular
disease in normal-weight men.

2) Metabolism 2002 Jul;51(7):864-70
Volek JS, et al. Body composition and hormonal responses to a
carbohydrate-restricted diet.

(in the second, they indicate an *increase* in lean body mass, which puts
paid to Ms. Tallmadge's dippy theory)


As well, there is the following Kuwaiti 12-week study which showed a
*transient* increase in urea and uric acid only; after 4 weeks, the level
dropped back to normal.


Effect of Ketogenic Diet in the Reduction of Body Weight in Obese Patients.

Hussein M Dashti, Yousef Y Bo-Abbas, Sami K Asfar, Abdulla I Behbahani,
Mousa A Khoursheed, Hilal M Al-Sayer, Nagi S Al-Zaid Dept of Surgery, Fac of
Med, Kuwait Univ, Kuwait, Kuwait, Kuwait; Dept of Med, Fac of Med, Kuwait
Univ, Kuwait, Kuwait, Kuwait; Dept of Physiology, Fac of Med, Kuwait Univ,
Kuwait, Kuwait, Kuwait

To determine the long-term effects of ketogenic diet (consisting of 30 gms
carbohydrate, 1gm/kg body weight protein, 20% polysaturated, 80%
polyunsaturated and monounsaturated fat) in obese patients following the
administration for a period of twelve weeks. In this study sixty-three obese
patients (body mass index > 30kg/m2) with a high glucose and cholesterol
level were selected. Female: male ratio was 2:1. The fasting blood sugar,
total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, Na+, K+,
urea, uric acid and creatinine levels of these patients were determined
before and after the administration of the ketogenic diet. Changes in these
parameters were monitored at weekly interval for twelve weeks. There was a
significant reduction in all the parameters examined (p <0.001), except in
the level of Na+, K+, and creatinine, while the level of HDL-cholesterol
significantly increased. The level of urea and uric acid increased
transiently during the 2nd and the 3rd week and returned to normal level
during the 4th week. These levels remained constant from 4th to the 12th
week. Interestingly, there was a significant reduction in body weight (99
+/- 2.8 to 80 + 3.0 kg). The level of triglycerides (2.74 +/-1.2 to 1.2 +/-
0.5 mmol/L), cholesterol (5.4 +/- 0.14 to 4.72 +/- 0.28 mmol/L), LDL (4.13
+/- 0.14 to 3.1 + 0.12 mmol/L) and glucose (7.7 +/- 0.5 to 5.2 +/- 0.43
mmol/L) also significantly decreased. The level of HDL showed a
significant increase from 1.08 +/- 1.01 to 1.3 +/- 0.1 mmol/L.

In conclusion: - Ketogenic diet acts as a natural therapy for weight
reduction in obese patients. It significantly reduced the level of
triglycerides, total cholesterol, LDL-cholesterol and glucose whereas the
level of HDL increased in these patients. The side effect of other drugs
commonly used for the reduction of body weight in such patients is not
observed in patients who were on Ketogenic diet. These results indicate that
the administration of ketogenic diet for relatively long period is safe to
follow.