<<Disclaimer: Verify this information before applying it to your situation.>> First a little background. My husband and I have four children. Our youngest son Andrew was diagnosed (by biopsy)at 17 months, had all the classic symptoms of Celiac Disease. This is the first we had ever heard of Celiac Disease. Because of the genetic component of the disease, we had all the kids tested. Our other son,10 y.o. Brian, came back positive with the blood work, had a biopsy, positive for Celiac. I just received the HLA results today for the four kids and me,(my husband was sick so he didn't get tested when we did). Andrew, Brian, and one daughter came back with DQ2 positive. One daughter was DQ2 negative. All 4 kids were DQ8 negative. But heres the thing, I (mom) came back DQ8 positive and DQ2 negative. So here are my questions. 1. Since I am DQ2 negative, does this mean that my husband has to be DQ2 positive? 2. I know DQ2 is a fairly common gene, how common is DQ8? Has anyone else that had the testing had both genes? We were hoping that the gene test would at least tell us which side of the family it is on because their are people on both sides with symptoms. I am awaiting a call from the GI but were apprciate any wisdom that anyone has to share. Beth, Cincinnati