<<Disclaimer: Verify this information before applying it to your situation.>> Thanks to all who responded to my question. Responses were somewhat varied as to whether gene HLA-DQ8 is as much an indicator or celiac as HLA-DQ2. My gene test results came back showing I have 2 copies of gene HLA-DQ8. Didn't do the stool sensitivity test because I've been gluten free for 15 months. Blood screens came back normal and no biopsy done because I wasn't eating gluten, thanks to the CSA/USA website, for almost a month before visiting the Dr. Here are the responses I received. 1. HLA-DQ2 gene is present in about 90% of diagnosed celiacs. HLA-DQ8 is the gene present in about 8 percent. 2. According to a number of papers at the Baltimore conference, HLA-DQ2 is the most important celiac gene, with HLA-DQ8 next most important. Both DQ2 and DQ8 together account for only about half of celiac occurences, with other genes unknown. Genetics account for about 70% of celiac incidence (My father could have been celiac). 30% of identical twins with one celiac twin has a normal second twin. 3. The genes are one and the same. 4. A suggestion for another good site with knowledgeable people to answer questions. http://forums.delphi.com/celiac/messages 5. (Enterolab - Dr. Fine): DQ2 and DQ8 are different genes but both lead to gluten sensitivity and celiac disease. You are gluten sensitive and need to be off gluten. That is all you need to know. It does not matter what your intestine looks like under a microscope. It makes you sick to eat it.