Diane, Regarding the timing of these oil supplements, I take them together. I space the borage out because I was told to, and I space the fish oil out because the box says to take each dose with a meal. Also, because I also take other vitamins, it's easier to space them out. I tend to have a sluggish thyroid, and my concern is that these highly unsaturated oils could be making this problem worse. There is so much conflicting information! Atkins, Eades, Crayhon, and others say omega-3 oils are excellent for thyroid function, while Ray Peat says omega-3 and omega-6 oils are toxic and detrimental to the thyroid. He claims carrots, coconut, milk, cheese, potatoes and fruit are very important for thyroid function and that meats, eggs and fatty fish contain harmful, toxic fats that impede thyroid function. I do know that my tsh has risen while low- carbing and my free t-3 levels have dropped dramatically, but I am hoping that this is just my body adjusting/compensating for fat loss. Any thoughts? Adrienne