<<Disclaimer: Verify this information before applying it to your situation.>> Hi All-- Is there anyone on the list who knows if there is a connection between CD and mastocytosis (an overabundance of mast cells in the body, which produce histamine as reactions to foods, viruses, bacteria)? Sorry for yet another question about "connections," but as a result of a skin biopsy done to rule out DH, results indicated an elevated level of IgM, which is rare - especially since the biopsy was done a month after the rash cleared. Symptoms of mastocytosis include malabsorption, gastrointestinal problems, rashes, and rarely, mast cell leukemia. Mastocytosis is a rare disorder, classified as an "orphan" disease, but because it shares so many symptoms with CD, I thought perhaps someone would have some knowledge of it. Thanks for any info anyone can share. I'll summarize. Ayn Gilliland Topeka, Kansas