<<Disclaimer: Verify this information before applying it to your situation.>> Finally, my summary on biopsy. My original question was . ... When someone has been given blood tests (1 positive and 1 negative), then is given a biopsy which is negative, does that mean that person does not have Celiac Disease and never will? Or does that mean that at this time there has not been a trigger and CD has not yet shown up but could later in life?? The very best advise was to contact Dr. Cynthia Rudert who is a Celiac expert through the Clan Thompson web site. Go to this web site: http://www.idsl.net/celiac/ E-mail Clan Thompson (it is a celiac family of 4) and ask how you can get that answered by Dr. Rudert. My reply from Dr. Rudert was: Unfortunately I would like to have a little more information to completely answer this question. I would like to know if the blood tests were positive, specifically, the anti-endomysial antibody, tissue transglutaminase or anti-gliadin antibody. Occasionally individuals may have "latent" Celiac disease and therefore normal biopsies could theoretically eventually become abnormal in genetically predisposed individuals if certain triggers occur. Also, if the biopsies were not obtained from the correct locations this could represent a false negative due to sampling error. In other words, if you don't biopsy in the location with the highest yield, you may miss the disease and if only one biopsy was obtained, I feel this is inadequate. It is my personal bias to take anywhere from 12 to 20 biopsies from the duodenum/jejunum. Other responses are: This just happened to me. I received negative results from the biopsy day before yesterday. I feel absolutely better off wheat as well as milk and maybe soy. Please let me know what you found out. I had a strong positive to the IgA test and negative to the IgA test. If the positive blood test was the antigliadin antibody IgG, and the negative was the IgA, and the biopsy was negative, this means they don't have Celiac now, but if they have inherited the genes, they could develop it down the road. I would like to relate my experience regarding having my son tested genetically to determine if he had the potential to develop Celiac disease in the future. What helped me the most with reaching this goal was an ad in Ann Whelan's Gluten Free Newsletter for Specialty Laboratories in California and they had the Celiac Disease GenotypR test (#1078) listed. In addition they had the Celiac Disease EvaluatR (#1077) which includes Transglutaminase IgA autoantibodies, IgG & IgA gliadin antibodies, IgA endomysial autoantibodies, and IgA reticulin autoantibodies. If anyone finds other info on the subject, please keep us all informed!! Thanks for all of the great help, Krista