I have a Natural 4,000 Ergonomic keyboard (not wireless), with the same 
peculiarity. It's got a thirteenth function key, which locks and unlocks the 
other function keys. I've never been quite sure why this would be desirable 
except that, when I slide my keyboard tray in, the function keys are 
sometimes depressed by a lip or overhang that's on the front of my desk. 
Maybe some people tend to accidentally push their keyboard trays in, like 
when they reach forward to answer the phone, and this is a feature they 
want?

Albert writes:

I have also run into an issue with my wireless keyboard whereby I have 
accidently pressed a key in the top right-hand corner of the keyboard that 
seems to turn off the Function keys.  I don't quite know why that would be 
necessary, and I've not seen it on any other keyboard. 


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