Let me expand upon this question by suggesting that one ought to have 
multiple browsers (and, yes, screen readers) on their PCs.
True, one will be the default browser; but I have long ago discovered that 
certain sites and/or pages work (for me) better with a certain browser and 
perhaps even a given screen reader.
And, if you use a site regularly, it may be well worth the effort what 
works best for you -- and I mean for you, not me or a bunch of other 
people who aren't in  your shoes or use a pc in the way you happpen to. 


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