Anya,
If anti-thyroid drugs are stopped suddenly there is possibility of provoking
hyper symptoms. Neo-Mercazole's mode of action is to inhibit the formation
of thyroid hormone precursors by decreasing the uptake of iodide. With a
reduced amount of thyroid hormones in the system-- the gland is stimulated
by TSH to secrete more hormones. Thus, the TSH should be higher than
baseline. With sudden withdrawal of the drug and an elevated stimulation by
TSH-- you see more symptoms. I wonder how long your mom has been taking the
drug. Risk of Side-effects increases with age past 40yo. Perhaps it is
better to ask your specialist what her treatment options are. There are ways
to control her symptoms in the short term and other modes to control her
thyroid in the long term.
Good luck..
Greg De Guzman
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