Hello to everybody! It's been a long time since I contributed to the List, but I wanted to share this (and I apologize in advance if it is long).
 
 I was diagnosed with Hashimoto's in 1997, and took Synthroid from '97 to 2001, with part of that time involved in taking it with 25 mcg. of Cytomel. Since June of '01, I have been on Sustained-Release T3 (no thyroxine at all), and overall I'd have to say it's been a great success. Over the years, when I feel some of the old hypo symptoms returning, I'd "cycle" down on the SRT3 and then go back up again. Usually I know when to start going up when I get the chest pain of costochondritis, or I feel weepy and cannot concentrate at all.
 
 Anyway, over the last year or so, I'd been holding steady at 90 mcg. of SRT3 twice a day; over the last two months, I'd become aware that I was sweating even more than I used to. All my life I've sweat profusely at any exertion; it just seemed now that it took a lot less exertion, AND a lot more sweat would come out. As I had read somewhere that excess sweating can be a symptom of being hyper, I became concerned. Then, on the web a few days ago, I came across a condition called "Plummer's Nails" (There's a Greek term for the same thing, but I don't remember now what it is), whereby the nails (fingers or toes) start to "disassociate" from the nail beds, and the nails take on a "bowl-like" shape. This can be caused by hyperthryoidism (which, in my case, would mean overdosing on the replacement hormone). Several of my fingernails fit that description, so I decided it was a good time to "cycle down" on the SRT3. So, I got down to 45 mcg. (x 2/day), and today felt very weepy, and so I decided to start increasing the dose.
 
 Here's the rub: there was a death in my immediate family in mid-September, and I'm wondering if this complicates the metabolic picture. If I was taking any thryoxine at all, I'd have assumed that under deep stress, the Thyroxine would convert to reverse T3, and I would start getting the symptoms of inadequate replacement. But as if I've just been on SRT3, well . . . I don't know. A weight gain of 5 pounds over the last month seems intractable.
 
 Any thoughts, anyone?
 
 Thanks,
 
 Edward Reisman
  
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