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Subject:
From:
Anya Salih <[log in to unmask]>
Reply To:
Thyroid Discussion Group <[log in to unmask]>
Date:
Tue, 13 Feb 2007 09:43:03 +1100
Content-Type:
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>
>   1. low TSH - need some advice!
>

Dear Greg,

Thank you for the explanation. Mum hadn't stopped taking neo- 
mercazole for the last 6 years. Except for a short time following an  
operation on kidney in December. Her specialist doesn't think that  
the levels are too abnormal because T3 and T4 were within normal  
levels (only TSH was 0.045). I dug up her previous test from 2000,  
and it was also the same level! So the doctor said that all's well.  
Yet mum is obviously suffering very thyroid-disfunction type symptoms  
which are much worse than previously. I guess what you suggest is  
that the operation might have caused the levels to jump.  Another  
complication was that her adrenal gland was resected but that, I was  
told, wouldn't cause the symptoms that she has. Reading the archives,  
it seems that even when blood tests are relatively normal, there can  
be hyperthyroidism but I haven't understood yet how does then one  
find out and stabilize the hormones.

All the best
Anya




>
> Date:    Wed, 7 Feb 2007 23:01:23 +0800
> From:    Greg De Guzman <[log in to unmask]>
> Subject: Re: low TSH - need some advice!
>
> Anya,
>
> If anti-thyroid drugs are stopped suddenly there is possibility of  
> provoking
> hyper symptoms. Neo-Mercazole's mode of action is to inhibit the  
> formation
> of thyroid hormone precursors by decreasing the uptake of iodide.  
> With a
> reduced amount of thyroid hormones in the system-- the gland is  
> stimulated
> by TSH to secrete more hormones. Thus, the TSH should be higher than
> baseline. With sudden withdrawal of the drug and an elevated  
> stimulation by
> TSH-- you see more symptoms. I wonder how long your mom has been  
> taking the
> drug. Risk of Side-effects increases with age past 40yo. Perhaps it is
> better to ask your specialist what her treatment options are. There  
> are ways
> to control her symptoms in the short term and other modes to  
> control her
> thyroid in the long term.
>
> Good luck..
>
>
> Greg De Guzman
>
>









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