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Subject:
From:
"Namaste, Liz" <[log in to unmask]>
Reply To:
Paleolithic Eating Support List <[log in to unmask]>
Date:
Sun, 1 Sep 2002 03:37:24 EDT
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Another twist on protein and kidney health -- as I've said before, abrupt
changes in diet composition will change metabolic markers, but the body works
it out in time.
In a message dated 8/15/02 7:28:24 AM, [log in to unmask] writes:

>there is the following Kuwaiti 12-week study which showed a
>
>*transient* increase in urea and uric acid only; after 4 weeks, the level
>
>dropped back to normal.
>
>
>
>
>
>Effect of Ketogenic Diet in the Reduction of Body Weight in Obese Patients.
>
>
>
>Hussein M Dashti, Yousef Y Bo-Abbas, Sami K Asfar, Abdulla I Behbahani,
>
>Mousa A Khoursheed, Hilal M Al-Sayer, Nagi S Al-Zaid Dept of Surgery, Fac
>of
>
>Med, Kuwait Univ, Kuwait, Kuwait, Kuwait; Dept of Med, Fac of Med, Kuwait
>
>Univ, Kuwait, Kuwait, Kuwait; Dept of Physiology, Fac of Med, Kuwait Univ,
>
>Kuwait, Kuwait, Kuwait
>
>
>
>To determine the long-term effects of ketogenic diet (consisting of 30
>gms
>
>carbohydrate, 1gm/kg body weight protein, 20% polysaturated, 80%
>
>polyunsaturated and monounsaturated fat) in obese patients following the
>
>administration for a period of twelve weeks. In this study sixty-three
>obese
>
>patients (body mass index > 30kg/m2) with a high glucose and cholesterol
>
>level were selected. Female: male ratio was 2:1. The fasting blood sugar,
>
>total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, Na+,
>K+,
>
>urea, uric acid and creatinine levels of these patients were determined
>
>before and after the administration of the ketogenic diet. Changes in these
>
>parameters were monitored at weekly interval for twelve weeks. There was
>a
>
>significant reduction in all the parameters examined (p <0.001), except
>in
>
>the level of Na+, K+, and creatinine, while the level of HDL-cholesterol
>
>significantly increased. The level of urea and uric acid increased
>
>transiently during the 2nd and the 3rd week and returned to normal level
>
>during the 4th week. These levels remained constant from 4th to the 12th
>
>week. Interestingly, there was a significant reduction in body weight (99
>
>+/- 2.8 to 80 + 3.0 kg). The level of triglycerides (2.74 +/-1.2 to 1.2
>+/-
>
>0.5 mmol/L), cholesterol (5.4 +/- 0.14 to 4.72 +/- 0.28 mmol/L), LDL (4.13
>
>+/- 0.14 to 3.1 + 0.12 mmol/L) and glucose (7.7 +/- 0.5 to 5.2 +/- 0.43
>
>mmol/L) also significantly decreased. The level of HDL showed a
>
>significant increase from 1.08 +/- 1.01 to 1.3 +/- 0.1 mmol/L.
>
>
>
>In conclusion: - Ketogenic diet acts as a natural therapy for weight
>
>reduction in obese patients. It significantly reduced the level of
>
>triglycerides, total cholesterol, LDL-cholesterol and glucose whereas the
>
>level of HDL increased in these patients. The side effect of other drugs
>
>commonly used for the reduction of body weight in such patients is not
>
>observed in patients who were on Ketogenic diet. These results indicate
>that
>
>the administration of ketogenic diet for relatively long period is safe
>to
>
>follow.
>
>


Namaste, Liz
<A HREF="http://www.csun.edu/~ecm59556/Healthycarb/index.html">
http://www.csun.edu/~ecm59556/Healthycarb/index.html</A>


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