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Date:
Mon, 4 Dec 2000 05:35:21 -0700
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  I think I discovered this for myself in  1950.   WHEN    i
QUIT SUGAR AND WHITE FLOUR!

HOPEFULLY YOU  MAY FIND IT INTERESTING.

Regards,   Lorenzo

Quoted Article follows:


 ........... BIOLOGY_AGING
AGE Breakers
Rupturing the body's sugar-protein bonds might turn back the
clock




LONDON--For all the promise of anti-aging creams and
therapies, nothing has ever restored the vigor of youth or
even delayed the inevitable process of growing old.
Researchers now claim to have developed a compound that
might rejuvenate hearts and muscles--by breaking the stiff
sugar-protein bonds that accumulate as we get older.

Anthony Cerami of the Kenneth S. Warren Laboratories in
Tarrytown, N.Y., suspected some 30 years ago that sugar
affects how the body ages, based on observations of
diabetics, who age rapidly. Sugars are an essential source
of energy, but once in circulation they can act as molecular
glue, attaching themselves to the amino groups in tissue
proteins and cross-linking them into hard yellow-brown
compounds known as advanced glycation end products, or AGEs.

Indeed, after years of bread, noodles and cakes, human
tissues inevitably become rigid and yellow with pigmented
AGE deposits. For the most part, piling on dark pigments in
the teeth, bones and skin is harmless. But where glucose
forms tight bonds with the long-lived protein collagen, the
result is a constellation of changes, including thickened
arteries, stiff joints, feeble muscles and failing
organs--the hallmarks of a frail old age. (Diabetics age
prematurely because sugar-driven damage acquires breakneck
speed, raising their levels of AGE-infused collagen to those
of elderly people.) "The evidence that sugar cross-linking
increases as we age is persuasive," comments Jerry W. Shay
of the University of Texas Southwestern Medical Center at
Dallas. "There are diseases associated with increased
glycation, which are directly related to increased age."
Sugar's connection with AGE formation may be one reason
caloric restriction might delay aging.
process that occurs in multiple systems. But," she warns,
"there won't be one silver bullet."


--Lisa Melton

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