A review on the study previously posted:

Rapid health improvements with a Paleolithic diet
http://www.proteinpower.com/drmike/saturated-fat/rapid-health-improvements-with-a-paleolithic-diet/

Steve

steve wrote:
> Hot off the press.
> 
> Steve
> 
> -- 
> 
> http://www.ncbi.nlm.nih.gov/pubmed/19209185
> 
> Metabolic and physiologic improvements from consuming a paleolithic, 
> hunter-gatherer type diet.
> Frassetto LA, Schloetter M, Mietus-Synder M, Morris RC Jr, Sebastian A.
> 
> 1Department of Medicine, University of California San Francisco School 
> of Medicine, San Francisco, CA, USA.
> 
> Background:The contemporary American diet figures centrally in the 
> pathogenesis of numerous chronic diseases-'diseases of civilization'. We 
> investigated in humans whether a diet similar to that consumed by our 
> preagricultural hunter-gatherer ancestors (that is, a paleolithic type 
> diet) confers health benefits.Methods:We performed an outpatient, 
> metabolically controlled study, in nine nonobese sedentary healthy 
> volunteers, ensuring no weight loss by daily weight. We compared the 
> findings when the participants consumed their usual diet with those when 
> they consumed a paleolithic type diet. The participants consumed their 
> usual diet for 3 days, three ramp-up diets of increasing potassium and 
> fiber for 7 days, then a paleolithic type diet comprising lean meat, 
> fruits, vegetables and nuts, and excluding nonpaleolithic type foods, 
> such as cereal grains, dairy or legumes, for 10 days. Outcomes included 
> arterial blood pressure (BP); 24-h urine sodium and potassium excretion; 
> plasma glucose and insulin areas under the curve (AUC) during a 2 h oral 
> glucose tolerance test (OGTT); insulin sensitivity; plasma lipid 
> concentrations; and brachial artery reactivity in response to 
> ischemia.Results:Compared with the baseline (usual) diet, we observed 
> (a) significant reductions in BP associated with improved arterial 
> distensibility (-3.1+/-2.9, P=0.01 and +0.19+/-0.23, P=0.05);(b) 
> significant reduction in plasma insulin vs time AUC, during the OGTT 
> (P=0.006); and (c) large significant reductions in total cholesterol, 
> low-density lipoproteins (LDL) and triglycerides (-0.8+/-0.6 (P=0.007), 
> -0.7+/-0.5 (P=0.003) and -0.3+/-0.3 (P=0.01) mmol/l respectively). In 
> all these measured variables, either eight or all nine participants had 
> identical directional responses when switched to paleolithic type diet, 
> that is, near consistently improved status of circulatory, carbohydrate 
> and lipid metabolism/physiology.Conclusions:Even short-term consumption 
> of a paleolithic type diet improves BP and glucose tolerance, decreases 
> insulin secretion, increases insulin sensitivity and improves lipid 
> profiles without weight loss in healthy sedentary humans.European 
> Journal of Clinical Nutrition advance online publication, 11 February 
> 2009; doi:10.1038/ejcn.2009.4.
> 
> PMID: 19209185 [PubMed - as supplied by publisher]
>