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Subject:
From:
Todd Moody <[log in to unmask]>
Reply To:
Paleolithic Eating Support List <[log in to unmask]>
Date:
Tue, 1 Jun 2004 10:34:41 -0400
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Bruce Merritt wrote:

>"100gms of glucose,fructose,surcose,and rcho from honey
>and orange juice all decreased phagocytic index by 39 to 57%"
>"Modest BG elevation 90 to 130 inhibits insulin-mediated active
>transport of AA resulting in cell dyfunction.
>Glucose tolerance rises 10% per decade,increasing glycation
>rate of all proteins including lymphoid tissue
>(accerating immune senescence and tumor tolerance)"ely1988.
>BM
>
>

Shouldn't that be "Glucose *intolerance*...etc"?

Incidentally, I thought of another angle on this.  A few months back I
did some speculating on paleo, lowcarb, and male sexual performance,
having noted that at age 50 I definitely do better in that department if
I keep carbs low and/or keep my stomach empty.  I note that these days
in the US we are bombarded with advertisements for Viagra, Levitra, and
Cialis, all "sexual enhancement" drugs for men.  I did a bit of reading
and learned that the biochemical mechanism of all three drugs is the
same:  they are phosphodiesterase-5 (PDE5) inhibitors.  The normal
function of the PDE5 enzyme is to undo an erection; it is normally
released in quantity after orgasm.  But it seems that as many men get
older they tend to have more PDE5 in circulation, and that causes
problems.  As you might expect, nothing is said about *why* many men
might have more PDE5 in circulation as they age, but it is well known
that erectile problems are very common among type 2 diabetics (type 1 as
well, but possibly for different reasons).  So I did a bit more digging
and, sure enough, discovered that insulin tends to trigger release of
the PDE series of enzymes (not just PDE5), so a rise in fasting insulin
levels could be expected to cause an increase in PDE5 levels.

I haven't seen this connection made explicityly by anyone else, but I'm
sure it's out there.

What's even more interesting is that cinnamon, fenugreek, and ginger are
traditional herbal aphrodisiacs, and all three are now known to improve
insulin sensitivity.

Todd Moody
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